Sigma-Aldrich 360457-18L-CS Acetonitrile - ≥99.5% (18L)

NOTE: This product can only be sold and shipped within Canada.

Acetonitrile (MeCN, ACN) is an aliphatic nitrile that is commonly used as a reaction solvent as well as a chemical intermediate in organic synthesis. In many chromatographic techniques, MeCN is used as a mobile phase solvent due to its low viscosity, high elution strength, and miscibility in water.

Acetonitrile can be used as a solvent in:      
-The solid-phase peptide synthesis.     

-The sialylation reactions.      

-The synthesis of copper nanoparticles by reduction of copper nitrate salt using NaBH₄. During the preparation, ACN acts as a protecting solvent, which prevents the oxidation of nanoparticles.      

-The preparation of diaryl selenides by Cu-catalyzed coupling reaction between aryl iodides and diphenyl diselenide. In this process, ACN also functions as a ligand for the copper catalyst to increase its catalytic activity.

CAS Number: 75-05-8

Synonym:   ACN, Cyanomethane, Ethyl nitrile, Methyl cyanide

Molecular Weight: 41.05 g/mol

Boiling Pt: 81-82°C 
Melting Pt: –45°C

Density: 0.786 g/mL at 25 °C

** SEE LINK TO SDS FOR MORE INFORMATION